human STAT4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human STAT4.
shAAV-224540
AAV-h-STAT4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human STAT4 (signal transducer and activator of transcription 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SLEB11
Description (Vector)
STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Gene ID
6775
Gene Name (Vector)
signal transducer and activator of transcription 4
Gene Symbol
STAT4
HGNC ID
HGNC:11365
ORF Size (aa)
2247
ORF Size (bp)
2247 bp
RefSeq ID
NM_003151
RefSeq Synonyms
NM_003151, NM_001243835, BC031212,
Species
human
UniGene ID
Hs.80642
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.