human ST8SIA2 shRNA silencing AAV

Name 
AAV-h-ST8SIA2-shRNA
Cat No 
shAAV-224482
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ST8SIA2.

shAAV-224482
AAV-h-ST8SIA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HsT19690; SIAT8-B; SIAT8B; ST8SIA-II; ST8SiaII; STX
Description (Vector)
ST8SIA2 is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29.
Gene ID
8128
Gene Name (Vector)
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Gene Symbol
ST8SIA2
HGNC ID
HGNC:10870
ORF Size (aa)
1128
ORF Size (bp)
1128 bp
RefSeq ID
NM_006011
RefSeq Synonyms
NM_006011, NM_001330416, BC096205, BC096204, BC096203, BC096202,
Species
human
UniGene ID
Hs.302341

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.