human ST8SIA1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ST8SIA1.
shAAV-224479
AAV-h-ST8SIA1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ST8SIA1 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GD3S; SIAT8; SIAT8-A; SIAT8A; ST8SiaI
Description (Vector)
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29.
Gene ID
6489
Gene Name (Vector)
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Gene Symbol
ST8SIA1
HGNC ID
HGNC:10869
ORF Size (aa)
1071
ORF Size (bp)
1071 bp
RefSeq ID
NM_003034
RefSeq Synonyms
NM_003034, NM_001304450, BC126162, BC117285,
Species
human
UniGene ID
Hs.408614
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.