human ST3GAL3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ST3GAL3.
shAAV-224459
AAV-h-ST3GAL3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ST3GAL3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EIEE15; MRT12; SIAT6; ST3GALII; ST3GalIII; ST3N
Description (Vector)
ST3GAL3 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12 (MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene.
Gene ID
6487
Gene Name (Vector)
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Gene Symbol
ST3GAL3
HGNC ID
HGNC:10866
ORF Size (aa)
1128
ORF Size (bp)
1128 bp
RefSeq ID
NM_006279
RefSeq Synonyms
NM_174971, NM_174970, NM_174969, NM_174968, NM_174967, NM_174966, NM_174965, NM_174964, NM_174963, NM_006279, NM_001270466, NM_001270465, NM_001270464, NM_001270463, NM_001270462, NM_001270461, NM_001270460, NM_001270459, BC050380,
Species
human
UniGene ID
Hs.597915
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.