human SPAG4 shRNA silencing AAV

Name 
AAV-h-SPAG4-shRNA
Cat No 
shAAV-224065
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SPAG4.

shAAV-224065
AAV-h-SPAG4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SPAG4 (sperm associated antigen 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CT127; SUN4
Description (Vector)
The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development.
Gene ID
6676
Gene Name (Vector)
sperm associated antigen 4
Gene Symbol
SPAG4
HGNC ID
HGNC:11214
ORF Size (aa)
1311
ORF Size (bp)
1311 bp
RefSeq ID
NM_003116
RefSeq Synonyms
NM_003116, NM_001317931, BC111378,
Species
human
UniGene ID
Hs.123159

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.