human SP110 shRNA silencing AAV

Name 
AAV-h-SP110-shRNA
Cat No 
shAAV-224037
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SP110.

shAAV-224037
AAV-h-SP110-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SP110 (SP110 nuclear body protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IFI41; IFI75; IPR1; VODI
Description (Vector)
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Gene ID
3431
Gene Name (Vector)
SP110 nuclear body protein
Gene Symbol
SP110
HGNC ID
HGNC:5401
ORF Size (aa)
1644
ORF Size (bp)
1644 bp
RefSeq ID
NM_004509
RefSeq Synonyms
NM_080424, NM_004510, NM_004509, NM_001185015, BC019059,
Species
human
UniGene ID
Hs.145150

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.