human SOX8 shRNA silencing AAV

Name
AAV-h-SOX8-shRNA

Cat No
shAAV-224032

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SOX8.

shAAV-224032

AAV-h-SOX8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SOX8 (SRY-box 8). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

SOX8 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).

Gene ID

30812

Gene Name (Vector)

SRY-box 8

Gene Symbol

SOX8

HGNC ID

HGNC:11203

ORF Size (aa)

1341

ORF Size (bp)

1341 bp

RefSeq ID

NM_014587

RefSeq Synonyms

NM_014587, BC031797,

Species

human

UniGene ID

Hs.243678

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.