human SOCS5 shRNA silencing AAV

Name 
AAV-h-SOCS5-shRNA
Cat No 
shAAV-223977
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SOCS5.

shAAV-223977
AAV-h-SOCS5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SOCS5 (suppressor of cytokine signaling 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CIS6; Cish5; CISH6; SOCS-5
Description (Vector)
SOCS5 contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.
Gene ID
9655
Gene Name (Vector)
suppressor of cytokine signaling 5
Gene Symbol
SOCS5
HGNC ID
HGNC:16852
ORF Size (aa)
1611
ORF Size (bp)
1611 bp
RefSeq ID
NM_014011
RefSeq Synonyms
NM_144949, NM_014011, BC032862,
Species
human
UniGene ID
Hs.468426

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.