human SNX6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SNX6.
shAAV-223962
AAV-h-SNX6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SNX6 (sorting nexin 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MSTP010; TFAF2
Description (Vector)
SNX6 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. SNX6 results in two transcripts encoding two distinct isoforms.
Gene ID
58533
Gene Name (Vector)
sorting nexin 6
Gene Symbol
SNX6
HGNC ID
HGNC:14970
ORF Size (aa)
873
RefSeq ID
NM_021249
RefSeq Synonyms
NM_152233, NM_021249, BC001798,
Species
human
UniGene ID
Hs.583855
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.