human SNX5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SNX5.
shAAV-223959
AAV-h-SNX5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SNX5 (sorting nexin 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
sorting nexin-5
Description (eCommerce)
Sorting nexin-5 (SNX5) is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. SNX5 functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis [taken from NCBI Entrez Gene (Gene ID: 27131)].
Description (Vector)
SNX5 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein binds to fanconi anemia complementation group A protein, but its function is unknown. SNX5 results in two transcript variants encoding the same protein.
Gene ID
27131
Gene Name (eCommerce)
sorting nexin 5
Gene Name (Vector)
sorting nexin 5
Gene Symbol
SNX5
HGNC ID
HGNC:14969
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1215
ORF Size (bp)
1215 bp
Protein Name (eCommerce)
Sorting nexin-5
RefSeq ID
NM_152227
RefSeq Synonyms
NM_152227, NM_014426, NM_001282454, BC143274, BC093980, BC093623, BC002724,
Research Areas
EGFR Signaling,Golgi Apparatus,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
Sorting nexin-5 (SNX5) is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. SNX5 functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis [taken from NCBI Entrez Gene (Gene ID: 27131)].
UniGene ID
Hs.316890
UniProt ID (eCommerce)
Q9Y5X3
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.