human SNX13 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SNX13.
shAAV-223918
AAV-h-SNX13-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SNX13 (sorting nexin 13). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGS-PX1
Description (Vector)
SNX13 encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.
Gene ID
23161
Gene Name (Vector)
sorting nexin 13
Gene Symbol
SNX13
HGNC ID
HGNC:21335
ORF Size (aa)
2874
ORF Size (bp)
2874 bp
RefSeq ID
NM_015132
RefSeq Synonyms
NM_015132, BC045667,
Species
human
UniGene ID
Hs.487648
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.