human SNX10 shRNA silencing AAV

Name
AAV-h-SNX10-shRNA

Cat No
shAAV-223912

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SNX10.

shAAV-223912

AAV-h-SNX10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNX10 (sorting nexin 10). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

OPTB8

Description (Vector)

SNX10 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. SNX10 may play a role in regulating endosome homeostasis. Alternative splicing results in multiple transcript variants.

Gene ID

29887

Gene Name (Vector)

sorting nexin 10

Gene Symbol

SNX10

HGNC ID

HGNC:14974

ORF Size (aa)

606

RefSeq ID

NM_013322

RefSeq Synonyms

NM_013322, NM_001318199, NM_001318198, NM_001199838, NM_001199837, NM_001199835, BC034992, BC031050,

Species

human

UniGene ID

Hs.520714

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.