human SNRPD3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SNRPD3.
shAAV-223886
AAV-h-SNRPD3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
small nuclear ribonucleoprotein D3 polypeptide 18kDa; small nuclear ribonucleoprotein Sm D3; SMD3; Sm-D3; snRNP core protein D3
Description (eCommerce)
Small nuclear ribonucleoprotein D3 polypeptide 18kDa (Sm-D3) appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Sm-D3 binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P62318].
Description (Vector)
SNRPD3 belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis.
Gene ID
6634
Gene Name (eCommerce)
small nuclear ribonucleoprotein D3 polypeptide
Gene Name (Vector)
small nuclear ribonucleoprotein D3 polypeptide
Gene Symbol
SNRPD3
HGNC ID
HGNC:11160
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
381
Protein Name (eCommerce)
Small nuclear ribonucleoprotein Sm D3
RefSeq ID
NM_004175
RefSeq Synonyms
NM_004175, NM_001278656, BC003150, BC000457,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Small nuclear ribonucleoprotein D3 polypeptide 18kDa (Sm-D3) appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Sm-D3 binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P62318].
UniGene ID
Hs.356549
UniProt ID (eCommerce)
P62318
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.