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human SNRNP27 shRNA silencing AAV

Name 
AAV-h-SNRNP27-shRNA
Cat No 
shAAV-223862
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SNRNP27.

shAAV-223862
AAV-h-SNRNP27-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNRNP27 (small nuclear ribonucleoprotein U4/U6.U5 subunit 27). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
27K; RY1
Description (Vector)
SNRNP27 encodes a serine/arginine-rich (SR) protein. SR proteins play important roles in pre-mRNA splicing by facilitating the recognition and selection of splice sites. The encoded protein associates with the 25S U4/U6.U5 tri-snRNP, a major component of the U2-type spiceosome. The expression of this gene may be altered in cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1) retrovirus. A pseudogene of this gene is located on the long arm of chromosome 5. Alternatively spliced transcript variants have been observed for this gene.
Gene ID
11017
Gene Name (Vector)
small nuclear ribonucleoprotein U4/U6.U5 subunit 27
Gene Symbol
SNRNP27
HGNC ID
HGNC:30240
ORF Size (aa)
468
RefSeq ID
NM_006857
RefSeq Synonyms
NM_006857, BC017890,
Species
human
UniGene ID
Hs.54649

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.