human SNIP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SNIP1.
shAAV-223832
AAV-h-SNIP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SNIP1 (Smad nuclear interacting protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PMRED
Description (Vector)
SNIP1 encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).
Gene ID
79753
Gene Name (Vector)
Smad nuclear interacting protein 1
Gene Symbol
SNIP1
HGNC ID
HGNC:30587
ORF Size (aa)
1191
ORF Size (bp)
1191 bp
RefSeq ID
NM_024700
RefSeq Synonyms
NM_024700, BC027040,
Species
human
UniGene ID
Hs.471951
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.