human SMYD2 shRNA silencing AAV

Name
AAV-h-SMYD2-shRNA

Cat No
shAAV-223798

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SMYD2.

shAAV-223798

AAV-h-SMYD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SMYD2 (SET and MYND domain containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

histone methyltransferase SMYD2; HSKM-B; KMT3C; lysine N-methyltransferase 3C; N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2; zinc finger, MYND domain containing 14; ZMYND14

Description (eCommerce)

SET- and MYND-containing protein 2 (SMYD2) functions as a histone methyltransferase and has been reported to methylate p53 and histone H3.

Description (Vector)

SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 (PubMed 16805913)).(supplied by OMIM, Nov 2008)

Gene ID

56950

Gene Name (eCommerce)

SET and MYND domain containing 2

Gene Name (Vector)

SET and MYND domain containing 2

Gene Symbol

SMYD2

HGNC ID

HGNC:20982

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

819

Protein Name (eCommerce)

N-lysine methyltransferase SMYD2

RefSeq ID

NM_020197

RefSeq Synonyms

NM_020197, BC098335, BC098305, BC098276, BC098133, BC049367,

Research Areas

Chromatin Remodeling,DNA Damage/Repair,Histone Modification,Methyltransferase,Neurobiology,p53 Signaling,RNA Binding,Signal Transduction,Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

signal_transduction,cell_biology,genetics,transcription_translation,cell_biology,neurobiology,signal_transduction,genetics,transcription_translation,cell_biology

Species

human

Target Sentence

SET- and MYND-containing protein 2 (SMYD2) functions as a histone methyltransferase and has been reported to methylate p53 and histone H3.

UniGene ID

Hs.66170

UniProt ID (eCommerce)

Q9NRG4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.