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human SMTN shRNA silencing AAV

Name 
AAV-h-SMTN-shRNA
Cat No 
shAAV-223779
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SMTN.

shAAV-223779
AAV-h-SMTN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SMTN (smoothelin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
SMTN encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. SMTN is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Gene ID
6525
Gene Name (Vector)
smoothelin
Gene Symbol
SMTN
HGNC ID
HGNC:11126
ORF Size (aa)
2748
ORF Size (bp)
2748 bp
RefSeq ID
NM_006932
RefSeq Synonyms
NM_134270, NM_134269, NM_006932, NM_001207018, NM_001207017, BC034237,
Species
human
UniGene ID
Hs.149098

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.