human SMCR7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MIEF2.
shAAV-223743
AAV-h-SMCR7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MIEF2 (mitochondrial elongation factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MID49; SMCR7
Description (Vector)
SMCR7 encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
125170
Gene Name (Vector)
mitochondrial elongation factor 2
Gene Symbol
MIEF2
HGNC ID
HGNC:17920
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
RefSeq ID
NM_139162
RefSeq Synonyms
NM_148886, NM_139162, NM_001144900, BC014973,
Species
human
UniGene ID
Hs.655555
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.