human SLPI shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SLPI.
shAAV-223682
AAV-h-SLPI-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SLPI (secretory leukocyte peptidase inhibitor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALK1; ALP; BLPI; HUSI; HUSI-I; MPI; WAP4; WFDC4
Description (Vector)
SLPI encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity.
Gene ID
6590
Gene Name (Vector)
secretory leukocyte peptidase inhibitor
Gene Symbol
SLPI
HGNC ID
HGNC:11092
ORF Size (aa)
399
RefSeq ID
NM_003064
RefSeq Synonyms
NM_003064, BC020708,
Species
human
UniGene ID
Hs.517070
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.