human SLCO1C1 shRNA silencing AAV

Name
AAV-h-SLCO1C1-shRNA

Cat No
shAAV-223629

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLCO1C1.

shAAV-223629

AAV-h-SLCO1C1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLCO1C1 (solute carrier organic anion transporter family member 1C1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

OATP-F; OATP1; OATP14; OATP1C1; OATPF; OATPRP5; SLC21A14

Description (Vector)

SLCO1C1 encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants.

Gene ID

53919

Gene Name (Vector)

solute carrier organic anion transporter family member 1C1

Gene Symbol

SLCO1C1

HGNC ID

HGNC:13819

ORF Size (aa)

2139

ORF Size (bp)

2139 bp

RefSeq ID

NM_017435

RefSeq Synonyms

NM_017435, NM_001145946, NM_001145945, NM_001145944, BC022461,

Species

human

UniGene ID

Hs.47261

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.