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human SLC6A2 shRNA silencing AAV

Name 
AAV-h-SLC6A2-shRNA
Cat No 
shAAV-223565
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC6A2.

shAAV-223565
AAV-h-SLC6A2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC6A2 (solute carrier family 6 member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NAT1; NET; NET1; SLC6A5
Description (Vector)
SLC6A2 encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Gene ID
6530
Gene Name (Vector)
solute carrier family 6 member 2
Gene Symbol
SLC6A2
HGNC ID
HGNC:11048
ORF Size (aa)
1854
ORF Size (bp)
1854 bp
RefSeq ID
NM_001043
RefSeq Synonyms
NM_001172504, NM_001172502, NM_001172501, NM_001043, BC156903,
Species
human
UniGene ID
Hs.78036

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.