human SLC5A12 shRNA silencing AAV

Name
AAV-h-SLC5A12-shRNA

Cat No
shAAV-223537

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLC5A12.

shAAV-223537

AAV-h-SLC5A12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC5A12 (solute carrier family 5 member 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SMCT2

Description (Vector)

Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 (PubMed 17692818)).(supplied by OMIM, Dec 2008)

Gene ID

159963

Gene Name (Vector)

solute carrier family 5 member 12

Gene Symbol

SLC5A12

HGNC ID

HGNC:28750

ORF Size (aa)

1191

ORF Size (bp)

1191 bp

RefSeq ID

NM_178498

RefSeq Synonyms

NM_178498, BC049207,

Species

human

UniGene ID

Hs.148907

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.