human SLC33A1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SLC33A1.
shAAV-223377
AAV-h-SLC33A1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SLC33A1 (solute carrier family 33 member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACATN; AT-1; AT1; CCHLND; SPG42
Description (Vector)
SLC33A1 is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
9197
Gene Name (Vector)
solute carrier family 33 member 1
Gene Symbol
SLC33A1
HGNC ID
HGNC:95
ORF Size (aa)
1650
ORF Size (bp)
1650 bp
RefSeq ID
NM_004733
RefSeq Synonyms
NM_004733, NM_001190992, BC014416,
Species
human
UniGene ID
Hs.478031
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.