human SLC30A4 shRNA silencing AAV

Name
AAV-h-SLC30A4-shRNA

Cat No
shAAV-223366

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLC30A4.

shAAV-223366

AAV-h-SLC30A4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC30A4 (solute carrier family 30 member 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

znT-4; ZNT4

Description (Vector)

Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 (PubMed 9354792)).(supplied by OMIM, Mar 2008)

Gene ID

7782

Gene Name (Vector)

solute carrier family 30 member 4

Gene Symbol

SLC30A4

HGNC ID

HGNC:11015

ORF Size (aa)

1290

RefSeq ID

NM_013309

RefSeq Synonyms

NM_013309, NM_001321036, BC026089,

Species

human

UniGene ID

Hs.162989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.