human SLC30A10 shRNA silencing AAV

Name 
AAV-h-SLC30A10-shRNA
Cat No 
shAAV-223363
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC30A10.

shAAV-223363
AAV-h-SLC30A10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC30A10 (solute carrier family 30 member 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HMDPC; HMNDYT1; ZnT-10; ZNT10; ZNT8; ZRC1
Description (Vector)
SLC30A10 is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene.
Gene ID
55532
Gene Name (Vector)
solute carrier family 30 member 10
Gene Symbol
SLC30A10
HGNC ID
HGNC:25355
ORF Size (aa)
1455
ORF Size (bp)
1455 bp
RefSeq ID
NM_018713
RefSeq Synonyms
NM_018713, BC146291,
Species
human
UniGene ID
Hs.679909

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.