human SLC25A46 shRNA silencing AAV

Name 
AAV-h-SLC25A46-shRNA
Cat No 
shAAV-223289
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC25A46.

shAAV-223289
AAV-h-SLC25A46-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC25A46 (solute carrier family 25 member 46). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HMSN6B; solute carrier family 25 member 46
Description (eCommerce)
Solute carrier family 25 member 46 (SLC25A46) is a mitochondrial solute carrier protein family member. It functions in promoting mitochondrial fission, and prevents the formation of hyperfilamentous mitochondria. Mutation of this gene results in neuropathy and optic atrophy [taken from NCBI Entrez Gene (Gene ID: 91137)].
Description (Vector)
SLC25A46 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 (PubMed 16949250)).(supplied by OMIM, Mar 2008)
Gene ID
91137
Gene Name (eCommerce)
solute carrier family 25 member 46
Gene Name (Vector)
solute carrier family 25 member 46
Gene Symbol
SLC25A46
HGNC ID
HGNC:25198
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
Protein Name (eCommerce)
Solute carrier family 25 member 46
RefSeq ID
NM_138773
RefSeq Synonyms
NM_138773, NM_001303250, NM_001303249, BC017169,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Solute carrier family 25 member 46 (SLC25A46) is a mitochondrial solute carrier protein family member. It functions in promoting mitochondrial fission, and prevents the formation of hyperfilamentous mitochondria. Mutation of this gene results in neuropathy and optic atrophy [taken from NCBI Entrez Gene (Gene ID: 91137)].
UniGene ID
Hs.75639
UniProt ID (eCommerce)
Q96AG3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.