human SLC25A20 shRNA silencing AAV

Name
AAV-h-SLC25A20-shRNA

Cat No
shAAV-223237

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SLC25A20.

shAAV-223237

AAV-h-SLC25A20-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC25A20 (solute carrier family 25 member 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CAC; CACT

Description (Vector)

SLC25A20 product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

Gene ID

788

Gene Name (Vector)

solute carrier family 25 member 20

Gene Symbol

SLC25A20

HGNC ID

HGNC:1421

ORF Size (aa)

906

RefSeq ID

NM_000387

RefSeq Synonyms

NM_000387, BC001689,

Species

human

UniGene ID

Hs.13845

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.