human SLC25A15 shRNA silencing AAV

Name 
AAV-h-SLC25A15-shRNA
Cat No 
shAAV-223226
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC25A15.

shAAV-223226
AAV-h-SLC25A15-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC25A15 (solute carrier family 25 member 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D13S327; HHH; ORC1; ORNT1
Description (Vector)
SLC25A15 is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome.
Gene ID
10166
Gene Name (Vector)
solute carrier family 25 member 15
Gene Symbol
SLC25A15
HGNC ID
HGNC:10985
ORF Size (aa)
906
RefSeq ID
NM_014252
RefSeq Synonyms
NM_014252, BC002702,
Species
human
UniGene ID
Hs.646645

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.