human SLC1A2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SLC1A2.
shAAV-223164
AAV-h-SLC1A2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SLC1A2 (solute carrier family 1 member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EAAT2; GLT-1; HBGT
Description (Vector)
SLC1A2 encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.
Gene ID
6506
Gene Name (Vector)
solute carrier family 1 member 2
Gene Symbol
SLC1A2
HGNC ID
HGNC:10940
ORF Size (aa)
1725
ORF Size (bp)
1725 bp
RefSeq ID
NM_004171
RefSeq Synonyms
NM_004171, NM_001252652, NM_001195728, BC132768,
Species
human
UniGene ID
Hs.502338
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.