human EXT2 Over-expression AAV

Name
AAV-h-EXT2

Cat No
AAV-208200

Availability
4-5 weeks

This is an AAV expressing Human EXT2.

AAV-208200

AAV-h-EXT2

Ready-to-use AAV expressing Human EXT2 (exostosin glycosyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SOTV; SSMS

Description (Vector)

EXT2 encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene ID

2132

Gene Name (Vector)

exostosin glycosyltransferase 2

Gene Symbol

EXT2

HGNC ID

HGNC:3513

ORF Size (aa)

2157

ORF Size (bp)

2157 bp

RefSeq ID

NM_000401

RefSeq Synonyms

NM_207122, NM_001178083, NM_000401, BC068545, BC010058,

Species

human

UniGene ID

Hs.368404

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.