human SKIV2L2 shRNA silencing AAV

Name 
AAV-h-SKIV2L2-shRNA
Cat No 
shAAV-223046
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SKIV2L2.

shAAV-223046
AAV-h-SKIV2L2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SKIV2L2 (Ski2 like RNA helicase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATP-dependent helicase SKIV2L2; ATP-dependent RNA helicase DOB1; ATP-dependent RNA helicase SKIV2L2; Dob1; exosome RNA helicase MTR4; fSAP118; functional spliceosome-associated protein 118; KIAA0052; Mtr4; Ski2 like RNA helicase 2; SKIV2L2; superkiller viralicidic activity 2-like 2; TRAMP-like complex helicase
Description (eCommerce)
SKIV2L2 is also known as hMtr4 and KIAA0052 and is part of the nuclear exosome involved in ribosomal RNA processing.
Gene ID
23517
Gene Name (eCommerce)
Mtr4 exosome RNA helicase
Gene Name (Vector)
Ski2 like RNA helicase 2
Gene Symbol
SKIV2L2
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3129
ORF Size (bp)
3129 bp
Protein Name (eCommerce)
Superkiller viralicidic activity 2-like 2
RefSeq ID
NM_015360
RefSeq Synonyms
NM_015360, BC113509, BC104996, BC028604,
Research Areas
Cell Biology,Gene Expression,Helicase Activity,mRNA Processing,mRNA Splicing,RNA Processing,Spliceosome
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
SKIV2L2 is also known as hMtr4 and KIAA0052 and is part of the nuclear exosome involved in ribosomal RNA processing.
UniGene ID
Hs.274531
UniProt ID (eCommerce)
P42285

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.