human SIGLEC5 shRNA silencing AAV

Name 
AAV-h-SIGLEC5-shRNA
Cat No 
shAAV-222991
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SIGLEC5.

shAAV-222991
AAV-h-SIGLEC5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SIGLEC5 (sialic acid binding Ig like lectin 5). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD170; CD33L2; OB-BP2; OBBP2; SIGLEC-5
Description (Vector)
SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Gene ID
8778
Gene Name (Vector)
sialic acid binding Ig like lectin 5
Gene Symbol
SIGLEC5
HGNC ID
HGNC:10874
ORF Size (aa)
1656
ORF Size (bp)
1656 bp
RefSeq ID
NM_003830
RefSeq Synonyms
NM_003830, BC029896,
Species
human
UniGene ID
Hs.310333

Recently Viewed Products

Ad-h-NDUFA4L2

Cat No: ADV-222955

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.