human SHFM1 shRNA silencing AAV

Name 
AAV-h-SHFM1-shRNA
Cat No 
shAAV-222941
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SEM1.

shAAV-222941
AAV-h-SHFM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SEM1 (SEM1, 26S proteasome complex subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DSS1; ECD; SHFD1; Shfdg1; SHFM1; SHSF1
Description (Vector)
The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.
Gene ID
7979
Gene Name (Vector)
SEM1, 26S proteasome complex subunit
Gene Symbol
SEM1
HGNC ID
HGNC:10845
ORF Size (aa)
213
RefSeq ID
NM_006304
RefSeq Synonyms
NM_006304, BC032782,
Species
human
UniGene ID
Hs.489201

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.