human SH3KBP1 shRNA silencing AAV

Name 
AAV-h-SH3KBP1-shRNA
Cat No 
shAAV-222909
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SH3KBP1.

shAAV-222909
AAV-h-SH3KBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SH3KBP1 (SH3 domain containing kinase binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD2BP3; CIN85; GIG10; HSB-1; HSB1; MIG18
Description (Vector)
SH3KBP1 encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
Gene ID
30011
Gene Name (Vector)
SH3 domain containing kinase binding protein 1
Gene Symbol
SH3KBP1
HGNC ID
HGNC:13867
ORF Size (aa)
1998
ORF Size (bp)
1998 bp
RefSeq ID
NM_031892
RefSeq Synonyms
NM_031892, NM_001184960, NM_001024666, BC015806,
Species
human
UniGene ID
Hs.444770

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.