human SH2D3C shRNA silencing AAV

Name 
AAV-h-SH2D3C-shRNA
Cat No 
shAAV-222885
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SH2D3C.

shAAV-222885
AAV-h-SH2D3C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SH2D3C (SH2 domain containing 3C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CHAT; NSP3; PRO34088; SHEP1
Description (Vector)
SH2D3C encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
10044
Gene Name (Vector)
SH2 domain containing 3C
Gene Symbol
SH2D3C
HGNC ID
HGNC:16884
ORF Size (aa)
2112
ORF Size (bp)
2112 bp
RefSeq ID
NM_005489
RefSeq Synonyms
NM_170600, NM_005489, NM_001252334, NM_001142534, NM_001142533, NM_001142532, NM_001142531, BC032365, BC027962,
Species
human
UniGene ID
Hs.306412

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.