human SGTB shRNA silencing AAV

Name 
AAV-h-SGTB-shRNA
Cat No 
shAAV-222876
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SGTB.

shAAV-222876
AAV-h-SGTB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SGTB (small glutamine rich tetratricopeptide repeat containing beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
beta-SGT; SGT2; small glutamine rich protein with tetratricopeptide repeats 2; Small glutamine-rich protein with tetratricopeptide repeats 2; small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; small glutamine-rich tetratricopeptide repeat-containing protein beta
Description (eCommerce)
Nuclear prelamin A recognition factor-like protein (NARFL) is a component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. NARFL seems to negatively regulate the level of HIF1A expression, although this effect could be indirect [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H6Q4].
Gene ID
54557
Gene Name (eCommerce)
small glutamine rich tetratricopeptide repeat containing beta
Gene Name (Vector)
small glutamine rich tetratricopeptide repeat containing beta
Gene Symbol
SGTB
HGNC ID
HGNC:23567
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
915
ORF Size (bp)
915 bp
Protein Name (eCommerce)
Small glutamine-rich tetratricopeptide repeat-containing protein beta
RefSeq ID
NM_019072
RefSeq Synonyms
NM_019072, BC012044,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Nuclear prelamin A recognition factor-like protein (NARFL) is a component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. NARFL seems to negatively regulate the level of HIF1A expression, although this effect could be indirect [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H6Q4].
UniGene ID
Hs.482301
UniProt ID (eCommerce)
Q96EQ0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.