human SGIP1 shRNA silencing AAV

Name
AAV-h-SGIP1-shRNA

Cat No
shAAV-222849

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SGIP1.

shAAV-222849

AAV-h-SGIP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SGIP1 (SH3 domain GRB2 like endophilin interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 (PubMed 15919751) and Uezu et al., 2007 (PubMed 17626015)).(supplied by OMIM, Mar 2008)

Gene ID

84251

Gene Name (Vector)

SH3 domain GRB2 like endophilin interacting protein 1

Gene Symbol

SGIP1

HGNC ID

HGNC:25412

ORF Size (aa)

2580

ORF Size (bp)

2580 bp

RefSeq ID

NM_032291

RefSeq Synonyms

NM_032291, NM_001308203, BC040516,

Species

human

UniGene ID

Hs.132121

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.