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human SGCE shRNA silencing AAV

Name 
AAV-h-SGCE-shRNA
Cat No 
shAAV-222843
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SGCE.

shAAV-222843
AAV-h-SGCE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SGCE (sarcoglycan epsilon). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DYT11; epsilon-SG; ESG
Description (Vector)
SGCE encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. SGCE is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
8910
Gene Name (Vector)
sarcoglycan epsilon
Gene Symbol
SGCE
HGNC ID
HGNC:10808
ORF Size (aa)
1314
ORF Size (bp)
1314 bp
RefSeq ID
NM_003919
RefSeq Synonyms
NM_003919, NM_001346720, NM_001346719, NM_001346717, NM_001346715, NM_001346713, NM_001301139, NM_001099401, NM_001099400, BC021709,
Species
human
UniGene ID
Hs.371199

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.