human SGCB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SGCB.
shAAV-222841
AAV-h-SGCB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SGCB (sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A3b; LGMD2E; SGC
Description (Vector)
SGCB encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
Gene ID
6443
Gene Name (Vector)
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Gene Symbol
SGCB
HGNC ID
HGNC:10806
ORF Size (aa)
957
RefSeq ID
NM_000232
RefSeq Synonyms
NM_000232, BC020709,
Species
human
UniGene ID
Hs.438953
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.