human SFRS15 shRNA silencing AAV

Name 
AAV-h-SFRS15-shRNA
Cat No 
shAAV-222797
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SCAF4.

shAAV-222797
AAV-h-SFRS15-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SCAF4 (SR-related CTD associated factor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTD-binding SR-like protein rA4; pre-mRNA splicing SR protein rA4; SFRS15; splicing factor serine alanine 15; splicing factor, arginine/serine-rich 15; SRA4; SR-like CTD-associated factor 4; SR-related and CTD-associated factor 4
Description (eCommerce)
SR-related CTD-associated factor 4 (SCAF4) may act to physically and functionally link transcription and pre-mRNA processing (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95104].
Description (Vector)
SCAF4 likely encodes a member of the arginine/serine-rich splicing factor family. A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing. Alternatively spliced transcript variants have been described.
Gene ID
57466
Gene Name (eCommerce)
SR-related CTD associated factor 4
Gene Name (Vector)
SR-related CTD associated factor 4
Gene Symbol
SCAF4
HGNC ID
HGNC:19304
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3441
ORF Size (bp)
3441 bp
Protein Name (eCommerce)
Splicing factor, arginine/serine-rich 15
RefSeq ID
NM_020706
RefSeq Synonyms
NM_020706, NM_001145445, NM_001145444, BC064990, BC052286, BC043353, BC014921,
Research Areas
mRNA Processing,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
SR-related CTD-associated factor 4 (SCAF4) may act to physically and functionally link transcription and pre-mRNA processing (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95104].
UniGene ID
Hs.17255
UniProt ID (eCommerce)
O95104

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.