human SEZ6L2 shRNA silencing AAV

Name
AAV-h-SEZ6L2-shRNA

Cat No
shAAV-222750

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SEZ6L2.

shAAV-222750

AAV-h-SEZ6L2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SEZ6L2 (seizure related 6 homolog like 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BSRPA; PSK-1

Description (Vector)

SEZ6L2 encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants.

Gene ID

26470

Gene Name (Vector)

seizure related 6 homolog like 2

Gene Symbol

SEZ6L2

HGNC ID

HGNC:30844

ORF Size (aa)

2430

ORF Size (bp)

2430 bp

RefSeq ID

NM_012410

RefSeq Synonyms

NM_201575, NM_012410, NM_001243333, NM_001243332, NM_001114100, NM_001114099, BC000567,

Species

human

UniGene ID

Hs.6314

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.