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human SERTAD3 shRNA silencing AAV

Name 
AAV-h-SERTAD3-shRNA
Cat No 
shAAV-222721
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SERTAD3.

shAAV-222721
AAV-h-SERTAD3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SERTAD3 (SERTA domain containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RBT1
Description (Vector)
SERTAD3 was identified in a yeast two-hybrid assay employing the second subunit of human replication protein A as bait. It is localized to the nucleus and its expression is significantly higher in cancer cell lines compared to normal cell lines. This protein has also been shown to be a strong transcriptional co-activator. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
Gene ID
29946
Gene Name (Vector)
SERTA domain containing 3
Gene Symbol
SERTAD3
HGNC ID
HGNC:17931
ORF Size (aa)
591
RefSeq ID
NM_013368
RefSeq Synonyms
NM_203344, NM_013368, BC050643, BC014061,
Species
human
UniGene ID
Hs.515412

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.