human SERPINF1 shRNA silencing AAV

Name
AAV-h-SERPINF1-shRNA

Cat No
shAAV-222707

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SERPINF1.

shAAV-222707

AAV-h-SERPINF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SERPINF1 (serpin family F member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EPC-1; OI12; OI6; PEDF; PIG35

Description (Vector)

SERPINF1 is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.

Gene ID

5176

Gene Name (Vector)

serpin family F member 1

Gene Symbol

SERPINF1

HGNC ID

HGNC:8824

ORF Size (aa)

1257

ORF Size (bp)

1257 bp

RefSeq ID

NM_002615

RefSeq Synonyms

NM_002615, NM_001329905, NM_001329904, NM_001329903, BC013984, BC000522,

Species

human

UniGene ID

Hs.694727

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.