human SERPINE2 shRNA silencing AAV

Name 
AAV-h-SERPINE2-shRNA
Cat No 
shAAV-222706
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SERPINE2.

shAAV-222706
AAV-h-SERPINE2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SERPINE2 (serpin family E member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GDN; GDNPF; PI-7; PI7; PN-1; PN1; PNI
Description (Vector)
SERPINE2 encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. SERPINE2 is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
Gene ID
5270
Gene Name (Vector)
serpin family E member 2
Gene Symbol
SERPINE2
HGNC ID
HGNC:8951
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
RefSeq ID
NM_006216
RefSeq Synonyms
NM_006216, NM_001136530, NM_001136528, BC042628, BC015663,
Species
human
UniGene ID
Hs.38449

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.