human SERBP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SERBP1.
shAAV-222630
AAV-h-SERBP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SERBP1 (SERPINE1 mRNA binding protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-55; CHD3IP; chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI-1 mRNA binding protein; PAI1 RNA-binding protein 1; PAIRBP1; PAI-RBP1; plasminogen activator inhibitor 1 RNA-binding protein; SERPINE1 mRNA-binding protein 1
Description (eCommerce)
Serpine1 mRNA binding protein 1(SERBP1) may play a role in the regulation of mRNA stability. SERBP1 binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NC51].
Gene ID
26135
Gene Name (eCommerce)
SERPINE1 mRNA binding protein 1
Gene Name (Vector)
SERPINE1 mRNA binding protein 1
Gene Symbol
SERBP1
HGNC ID
HGNC:17860
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1164
ORF Size (bp)
1164 bp
Protein Name (eCommerce)
Plasminogen activator inhibitor 1 RNA-binding protein
RefSeq ID
NM_015640
RefSeq Synonyms
NM_015640, NM_001018069, NM_001018068, NM_001018067, BC026916, BC020555, BC019273, BC017449, BC008045, BC003049, BC002488,
Research Areas
mRNA Binding,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Serpine1 mRNA binding protein 1(SERBP1) may play a role in the regulation of mRNA stability. SERBP1 binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NC51].
UniGene ID
Hs.530412
UniProt ID (eCommerce)
Q8NC51
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.