human SERAC1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SERAC1.
shAAV-222626
AAV-h-SERAC1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SERAC1 (serine active site containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
SERAC1 is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded protein plays a major role in mitochondrial function and intracellular cholesterol trafficking. Defects in this gene are a cause of 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
Gene ID
84947
Gene Name (Vector)
serine active site containing 1
Gene Symbol
SERAC1
HGNC ID
HGNC:21061
ORF Size (aa)
1965
ORF Size (bp)
1965 bp
RefSeq ID
NM_032861
RefSeq Synonyms
NM_032861, BC001705,
Species
human
UniGene ID
Hs.154706
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.