human SELM shRNA silencing AAV

Name 
AAV-h-SELM-shRNA
Cat No 
shAAV-222521
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SELENOM.

shAAV-222521
AAV-h-SELM-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SELENOM (selenoprotein M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SELM; SEPM
Description (Vector)
SELM encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. SELM is expressed in a variety of tissues, and the protein is localized to the perinuclear structures.
Gene ID
140606
Gene Name (Vector)
selenoprotein M
Gene Symbol
SELENOM
HGNC ID
HGNC:30397
ORF Size (aa)
438
RefSeq ID
NM_080430
RefSeq Synonyms
NM_080430, BC068004, BC030236, BC013421,
Species
human
UniGene ID
Hs.55940

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.