human SEC61G shRNA silencing AAV

Name 
AAV-h-SEC61G-shRNA
Cat No 
shAAV-222505
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SEC61G.

shAAV-222505
AAV-h-SEC61G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SEC61G (Sec61 translocon gamma subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SSS1
Description (Vector)
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene ID
23480
Gene Name (Vector)
Sec61 translocon gamma subunit
Gene Symbol
SEC61G
HGNC ID
HGNC:18277
ORF Size (aa)
207
RefSeq ID
NM_014302
RefSeq Synonyms
NM_014302, NM_001012456, BC051840, BC009480,
Species
human
UniGene ID
Hs.488282

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.