human VTN shRNA silencing AAV

Name 
AAV-h-VTN-shRNA
Cat No 
shAAV-222459
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VTN.

shAAV-222459
AAV-h-VTN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VTN (vitronectin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
V75; VN; VNT
Description (Vector)
VTN is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Gene ID
7448
Gene Name (Vector)
vitronectin
Gene Symbol
VTN
HGNC ID
HGNC:12724
ORF Size (aa)
1437
ORF Size (bp)
1437 bp
RefSeq ID
NM_000638
RefSeq Synonyms
NM_000638, BC005046,
Species
human
UniGene ID
Hs.2257

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.