human SCNN1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SCNN1B.
shAAV-222378
AAV-h-SCNN1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SCNN1B (sodium channel epithelial 1 beta subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BESC1; ENaCb; ENaCbeta; SCNEB
Description (Vector)
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.
Gene ID
6338
Gene Name (Vector)
sodium channel epithelial 1 beta subunit
Gene Symbol
SCNN1B
HGNC ID
HGNC:10600
ORF Size (aa)
1923
ORF Size (bp)
1923 bp
RefSeq ID
NM_000336
RefSeq Synonyms
NM_000336, BC036352,
Species
human
UniGene ID
Hs.414614
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.